DNA methylation of microRNA-375 in impaired glucose tolerance
نویسندگان
چکیده
منابع مشابه
DNA methylation of microRNA-375 in impaired glucose tolerance
In the present study, the expression levels and DNA methylation status of microRNA (miRNA)-375 in patients with impaired glucose tolerance (IGT) and type 2 diabetes mellitus (T2DM) were analyzed and the role of DNA methylation of miRNA-375 in the pathogenesis of T2DM was investigated. Compared with the miR-375 levels in patients with normal glucose tolerance (NGT; n=53), the samples from patien...
متن کاملPrevalence of diabetes, impaired fasting glucose and impaired glucose tolerance in patients with thalassemia major in Iran: A meta-analysis
Background: This study aimed to investigate the prevalence of diabetes, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) in Iranian patients with thalassemia major. Methods: The current study has been conducted based on PRISMA guideline. To obtain the documents, Persian and English scientific databases such as Magiran, Iranmedex, SID, Medlib, IranDoc, Scopus, PubMed, Scien...
متن کاملExpression and DNA methylation status of microRNA-375 in patients with type 2 diabetes mellitus.
Recent studies have shown that DNA methylation in the promoter of microRNA-375 (miR-375) downregulates its expression during tumorigenesis. However, it is not known if CpG methylation of the miR-375 promoter also has a role in the pathogenesis of type 2 diabetes mellitus (T2DM). In this study, the expression level and CpG methylation status of miR-375 in patients with T2DM were analyzed. Plasma...
متن کاملImpaired Glucose Tolerance
D of the category of impaired glucose tolerance by the National Diabetes Data Group (NDDG) and by the World Health Organization (WHO) has served to highlight the dearth of knowledge about the significance of glucose tolerance levels that fall short of being diagnostic of diabetes, but that are above normal if these are defined as glucose levels above the mean plus two standard deviations in hea...
متن کاملImpaired glucose tolerance in pregnancy.
Gestational diabetes mellitus is defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. It has been shown that the risk of adverse maternal, foetal, and neonatal outcomes in gestational diabetes mellitus is related to the degree of glucose intolerance and/or hyperglycaemia; gestational diabetes mellitus also has long-term sequelae for both the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2014
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2014.1816